FANTA reviewed evidence and country experiences in the management of acute malnutrition (MAM) in 11 South and Southeast Asia countries to examine how the different countries in the region have tackled acute malnutrition among children 6–59 months of age. The findings highlight the limited evidence base in South and Southeast Asia, while echoing the need for nutrition services in the region. The review also identified a number of recommendations needed to scale-up MAM around leadership and coordination, design of community-based management of acute malnutrition, adoption of standardized monitoring and evaluation of programs, and documentation and sharing of program experiences.